Does Furosemide Have a Role in the Management of Hypercalcemia?

  1. Susan B. LeGrand, MD
  1. From Cleveland Clinic, Cleveland, OH 44195.

    IN RESPONSE:

    Dr. Robey and colleagues question our conclusion that furosemide has no role other than management of fluid overload; however, we are not alone in this conclusion (1–3; http://www.uptodateonline.com). The fact that furosemide produces calciuria is not in question. The question is whether this translates into a practical therapy for malignant hypercalcemia. What we found was not a “wealth,” but a paucity of evidence for the value of furosemide and no evidence …

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