Empirical Use of Fluconazole in Critically Ill Patients: Good Study, but What Was the Hold-up?

  1. Dong Heun Lee, MD
  1. From Drexel University College of Medicine, Philadelphia, PA 19102.

    TO THE EDITOR:

    I was delighted to read the article by Schuster and colleagues (1) on the empirical use of fluconazole in critically ill patients in the intensive care unit (ICU). Although there was an 8-year delay between the completion and publication of the study, it is an excellent example of how a “negative” study still provides valuable data on making empirical antifungal treatment decisions in critically ill patients in the ICU. However, one needs to consider this 8-year gap and …

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