Brief Communication: Radiographic Contrast Infusion and Catecholamine Release in Patients With Pheochromocytoma

  1. Smita K. Baid, MD;
  2. Edwin W. Lai, BS;
  3. Robert A. Wesley, PhD;
  4. Alex Ling, MD;
  5. Henri J.L.M. Timmers, MD, PhD;
  6. Karen T. Adams, MSN, CRNP;
  7. Anna Kozupa, MD; and
  8. Karel Pacak, MD, PhD, DSc
  1. From Eunice Kennedy Shriver National Institute of Child Health and Human Development and Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland, and Radboud University, Nijmegen Medical Center, Nijmegen, the Netherlands.
    1. Appendix Figure.
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        Appendix Figure. Study flow diagram.

        CT = computed tomography.

        * Initial enrollment period.

        † Recommended to the authors to include more patients with solitary adrenal pheochromocytoma.

      • Figure.
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          Figure. Average norepinephrine and epinephrine levels, heart rate, and blood pressure in patients with pheochromocytoma compared with control participants before and after intravenous administration of computed tomography contrast.

          Arrows indicate the time of low-osmolar contrast injection. Bars represent 95% CIs. Number of patients with available data shown at each time point; there are no obvious outliers within the data.

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