Evaluating Test Strategies for Colorectal Cancer Screening: A Decision Analysis for the U.S. Preventive Services Task Force

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   Figure 1. Natural history of disease as modeled by the Microsimulation Screening Analysis and Simulation Model of Colorectal Cancer models.

   The opportunity to intervene in the natural history through screening is noted.
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   Figure 2. Colonoscopies and life-years gained (compared with no screening) for a cohort of 1000 forty-year-olds for 18 colonoscopy screening strategies that vary by start age, stop age, and screening interval.

   The numbers represent the following: age to beginage to stop screening, interval. MISCAN= Microsimulation Screening Analysis; SimCRC= Simulation Model of Colorectal Cancer.
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   Figure 3. Colonoscopies and life-years gained, by adherence level for the recommendable set of screening strategies.

   SENSA= Hemoccult SENSA; FIT= fecal immunochemical testing; FSIG= flexible sigmoidoscopy; MISCAN= Microsimulation Analysis Model; SimCRC= Simulation Model of Colorectal Cancer. *The numbers represent the following: age to beginage to stop screening, interval.
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   Appendix Figure 1. Microsimulation Screening Analysis and Simulation Model of Colorectal Cancer modeling of natural history into life history.
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   Appendix Figure 2. Microsimulation Screening Analysis and Simulation Model of Colorectal Cancer modeling of screening into life history.