Monitoring Cholesterol Levels: Understanding Variance and Finding the Most Useful Data

  1. William E. Cayley, MD, MDiv
  1. From University of Wisconsin School of Medicine and Public Health, Madison, WI 53705.

    TO THE EDITOR:

    The study by Glasziou and colleagues (1) finds that “noise” random variations during serial cholesterol level monitoring may be greater than the change in cholesterol levels due to a therapeutic effect. This points to the importance of what exactly has been tested …

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