Why Choose Serum Cystatin C Levels over Serum Creatinine Levels as a Serologic Marker of Kidney Function?

  1. Bryan Kestenbaum, MD, MS
  1. From the University of Washington, Harborview Medical Center, Seattle, WA 98104.

    IN RESPONSE:

    We chose serum cystatin C level as a serologic marker of kidney function for 3 reasons. First, serum cystatin C levels provide a more precise estimate of the GFR than do serum creatinine levels. In a recent pooled analysis, cystatin C levels accounted for 82% of the variation in radionucleotide-measured GFR, whereas serum creatinine …

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    1. Ann Intern Med August 19, 2008 vol. 149 no. 4 284
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