Correction: Reported Methodologic Quality and Discrepancies between Large and Small Randomized Trials in Meta-Analyses

  1. Lise L. Gluud, MD, DrMedSc;
  2. Kristian Thorlund, BSc;
  3. Christian Gluud, MD, DrMedSc;
  4. Lesley Woods, MD, PhD;
  5. Ross Harris, MSc; and
  6. Jonathan A.C. Sterne, MSc, PhD
  1. From Copenhagen University Hospital, DK-2100 Copenhagen, Denmark, and University of Bristol, Bristol BS8 2PR, United Kingdom.

    In 2001, we published a study on methodological quality and estimates of intervention effects (1). The results suggested that those estimates were exaggerated in small trials with inadequate allocation sequence (ratio of odds ratios for large vs. small trials, 0.49 [95% CI, 0.30 to 0.81]), …

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