Does Ascertainment Bias Affect Reports on the Incidence of Multidrug-Resistant, Community-Associated Methicillin-Resistant Staphylococcus aureus Infection?

  1. Binh An Diep, PhD; and
  2. Henry F. Chambers, MD
  1. From the University of California, San Francisco, San Francisco, CA 94110.

    IN RESPONSE:

    We thank Dr. Katz and colleagues for their concern regarding ascertainment bias of multidrug-resistant USA300 cases in our population-based survey. We reason that ascertainment bias would similarly affect the incidence estimates of multidrug-resistant and non–multidrug-resistant USA300 infections because they are indistinguishable to patients and clinicians. When compared with our previously published spatial distribution of multidrug-resistant USA300 infections according to San Francisco ZIP codes, non–multidrug-resistant …

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