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Association between Protein Levels and Mortality in Patients with Peripheral Arterial Disease
TO THE EDITOR:
I read with great interest the excellent article by Vidula and colleagues (1). The authors found that higher levels of d-dimer, C-reactive protein (CRP), and serum amyloid A were associated with higher all-cause and cardiovascular near-term mortality rates among 377 patients with peripheral arterial disease (PAD), 76 of whom died during 4 years of follow-up. Of particular interest is that elevation of CRP and serum amyloid A levels was a surrogate marker of death within 2 years after determination of these protein levels. The relative risk for death within 1 year after measurement of CRP and …
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