Meta-analysis: Effects of Adding Salmeterol to Inhaled Corticosteroids on Serious Asthma-Related Events

  1. Eric Bateman, MD;
  2. Harold Nelson, MD;
  3. Jean Bousquet, MD;
  4. Kenneth Kral, MS;
  5. Laura Sutton, PharmD;
  6. Hector Ortega, MD, ScD; and
  7. Steven Yancey, MS
  1. From University of Cape Town, Cape Town, South Africa; National Jewish Medical and Research Center, Denver, Colorado; Hôpital Arnaud de Villeneuve, Montpellier, France; and GlaxoSmithKline, Research Triangle Park, North Carolina.
    1. Figure 1.
      View larger version:
      Figure 1. Study flow diagram.

      GSK = GlaxoSmithKline.

      *Studies could contribute to more than 1 subanalysis.

    2. Figure 2.
      View larger version:
      Figure 2. Salmeterol (SAL) plus inhaled corticosteroids (ICS) versus ICS alone: risk difference for asthma-related hospitalization.

      *Number of events/total population.

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    1. Ann Intern Med July 1, 2008 vol. 149 no. 1 33-42
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