Systemic Effects of Nitrofurazone-Impregnated Urinary Catheters in Trauma Patients

  1. Jakob Stensballe, PhD
  1. From Copenhagen University Hospital, DK-2100 Copenhagen, Denmark.

    IN RESPONSE:

    We thank Dr. Stinnette for his interest. We found no evidence of adverse side effects, such as anemia and liver or respiratory failure, related to the nitrofurazone impregnation of the silicone catheter. This is in accordance with Marion-Landais and colleagues' (1) finding that nitrofurazone is not absorbed to the surrounding tissue or systemically. Furthermore, the observed adverse events in the study were found to be unrelated to the nitrofurazone impregnation and were more likely related to catheterization.

     
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    Jakob Stensballe, PhD

    Copenhagen University Hospital

    DK-2100 Copenhagen, Denmark

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    Article and Author Information

    • Potential Financial Conflicts of Interest: Dr. Stensballe is the recipient of an unrestricted research grant from Coloplast A/S.

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    Reference

    1. 1.↵
      1. Marion-LandaisG,
      2. HeotisJP,
      3. MertzJL,
      4. DiazJR,
      5. Van HartDC,
      6. NewsomJH
      et al.Non-absorption of nitrofurazone from the urethra in men.Curr Ther Res Clin Exp197619550-3pmid:820520
      Marion-Landais G, Heotis JP, Mertz JL, Diaz JR, Van Hart DC, Newsom JH, et al. Non-absorption of nitrofurazone from the urethra in men. Curr Ther Res Clin Exp. 1976;19:550-3. [PMID: 820520]
      Medline
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    1. Ann Intern Med March 18, 2008 vol. 148 no. 6 486
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