β-Blockers and Progression of Coronary Atherosclerosis

  1. Ilke Sipahi, MD; and
  2. Steven E. Nissen, MD
  1. From the Cleveland Clinic, Cleveland, OH 44195.

    IN RESPONSE:

    Dr. Dunaway's statement that “[p]rospective studies have shown no decreased incidence of myocardial infarction (MI) and stroke in patients treated with β-blockers versus placebo” is not true. The meta-analyses by Lindholm and colleagues (1) and Bradley and colleagues (2), involving more than 20 000 patients with hypertension, showed that β-blockers statistically …

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    1. Ann Intern Med March 4, 2008 vol. 148 no. 5 404-405
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