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Biological Significance of Anti–Cyclic Citrullinated Peptide Antibody in Rheumatoid Arthritis
- From the University of Southern California Keck School of Medicine, Los Angeles, CA 90033.
TO THE EDITOR:
I read the article by Nishimura and colleagues (1) with great interest. The use of anti-CCP testing makes RA diagnosis more accurate, which allows earlier detection in an attempt to avoid joint damage. However, the study has 3 potential pitfalls. First, up to 20% of new patients with RA are seronegative …
