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Agranulocytosis Induced by Nonchemotherapy Drugs
- Frank Andersohn, MD;
- Christine Konzen, MD; and
- Edeltraut Garbe, MD, PhD
- From Bremen Institute for Prevention Research and Social Medicine, 28539 Bremen, Germany, and Charité—Universitaetsmedizin Berlin, 10117 Berlin, Germany.
IN RESPONSE:
Most of the case reports suggested by Dr. Salem and colleagues were already included in our review (n = 10) (1). Six of the suggested reports were excluded because of use of cytotoxic drugs, pancytopenia, or a neutrophil count nadir of 0.5 × 109 cells/L or greater. Only 2 of the listed case reports (on carbutamide and nifedipine) were not identified because they were not listed as case reports in the MEDLINE publication type field. As causality is “possible” in these reports, the inclusion of these cases during the next database update will not cause any change …
