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Tumor Necrosis Factor–Blocking Agents in Polymyalgia Rheumatica and Giant Cell Arteritis
IN RESPONSE:
I am grateful to Drs. Salvarani and Hunder for raising the issue that their studies of infliximab in polymyalgia rheumatica and GCA were not designed to test a small treatment effect of the agent above that achieved from corticosteroid alone. If there is only a small treatment effect, a cost–benefit analysis is likely to conclude that infliximab does not have a clinically or …
