RSS Feeds
Vitamin D Compounds in Chronic Kidney Disease
TO THE EDITOR:
The meta-analysis by Palmer and colleagues (1) concludes that vitamin D compounds “do not consistently reduce PTH levels.” Parathyroid hormone suppression by “established vitamin D” is based on only 6 studies encompassing 187 patients. Of the 5 studies I could locate, none seemed to titrate vitamin D to achieve PTH level suppression or to have PTH level suppression as a primary goal. Active vitamin D treatment did cause significant improvements in the 3 studies examining bone histology and the 1 study examining bone mineral density. Meta-analyses must carefully assess the goals of trials from …
