Meta-analysis: Sequential Therapy Appears Superior to Standard Therapy for Helicobacter pylori Infection in Patients Naive to Treatment

  1. Nadim S. Jafri, MD, MSc;
  2. Carlton A. Hornung, PhD, MPH; and
  3. Colin W. Howden, MD
  1. From University of Louisville, Louisville, Kentucky, and Northwestern University Feinberg School of Medicine, Chicago, Illinois.
    1. Figure 1. ).
      View larger version:
      Figure 1. ). Identification of eligible randomized, controlled trials (RCTs
    2. Figure 2.
      View larger version:
      Figure 2. Funnel plot of all included studies.

      The vertical axis represents the line of no effect, and the horizontal axis represents the log risk ratio. The diagonal lines represent the 95% CI. The circles represent individual studies in the fixed-effects model. The diamond represents the pooled risk ratio and its 95% CI.

    Responses to this article

    • Reply to Dr. Gatta and colleagues
      • Colin W Howden and
      • Nadim S. Jafri, Colin W. Howden
      Ann Intern Med published online October 26, 2009
    • Sequential Treatment for Helicobacter pylori infection
      • Luigi Gatta and
      • Angelo Zullo, Francesco Di Mario, Dino Vaira
      Ann Intern Med published online October 26, 2009
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    1. Ann Intern Med June 17, 2008 vol. 148 no. 12 923-931
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