
We used a random-effects model and a weighted mean difference effect size to compare GH-treated and non–GH-treated participants. The black diamonds represents the summary effect size for the outcome of interest. Values greater than 0 indicate that results with GH treatment were higher than those without GH treatment. The studies are ordered by mean effect size. RER = respiratory exchange rate; RQ = respiratory quotient. *Low-dose group; data obtained from reference 50. †Low-dose GH. ‡High-dose GH. Data obtained from reference 50. §High-dose GH.