Incidence of Types of Cancer among HIV-Infected Persons Compared with the General Population in the United States, 1992–2003

  1. Pragna Patel, MD, MPH;
  2. Debra L. Hanson, MS;
  3. Patrick S. Sullivan, DVM, PhD;
  4. Richard M. Novak, MD;
  5. Anne C. Moorman, BSN, MPH;
  6. Tony C. Tong, MS;
  7. Scott D. Holmberg, MD, MPH;
  8. John T. Brooks, MD; and
  9. for the Adult and Adolescent Spectrum of Disease Project and HIV Outpatient Study Investigators*
  1. From the Centers for Disease Control and Prevention, Emory University, and Northrop Grumman Information Technology, Atlanta, Georgia, and the University of Illinois at Chicago, Chicago, Illinois.
    1. Appendix Figure 1. (
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      Appendix Figure 1. ( Annual incidence rates of 3 AIDS-definingtop row) and 9 non–AIDS-defining types of cancer among HIV-infected persons and the general population.

      Rates are unadjusted incidence rates per 100 000 person-years (PYs). Data for HIV-infected persons are drawn from the Adult and Adolescent Spectrum of Disease Project (ASD) and the HIV Outpatient Study (HOPS); general population data are estimated from Surveillance, Epidemiology, and End Results (SEER) program data, 1992–2003.

    2. Appendix Figure 2. (
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      Appendix Figure 2. ( Trends in annual incidence rates of 3 AIDS-definingtop row) and 9 non-AIDS-defining types of cancer among HIV-infected persons relative to the general population, using Poisson regression and nonlinear spline representations, 1992–2003.

      Data for HIV-infected persons are drawn from the Adult and Adolescent Spectrum of Disease Project (ASD) and the HIV Outpatient Study (HOPS); general population data are estimated from Surveillance, Epidemiology, and End Results (SEER) program data. P values of significant trends are depicted; dotted lines represent nonsignificant results. PY = person-year.

    3. Appendix Figure 3. (
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      Appendix Figure 3. ( Trends in standardized incidence rates of 3 AIDS-definingtop row) and 9 non–AIDS-defining types of cancer among HIV-infected persons and the general population, stratified by 3 periods from 1992 to 2003.

      Data for HIV-infected persons are drawn from the Adult and Adolescent Spectrum of Disease Project (ASD) and the HIV Outpatient Study (HOPS); general population data are estimated from Surveillance, Epidemiology, and End Results (SEER) program data.

    4. Appendix Figure 4.
      View larger version:
      Appendix Figure 4. Standardized rate ratios of 3 AIDS-defining (top row) and 9 non–AIDS-defining types of cancer among HIV-infected persons relative to the general population, stratified by 3 periods from 1992 to 2003.

      Data for HIV-infected persons are drawn from the Adult and Adolescent Spectrum of Disease Project (ASD) and the HIV Outpatient Study (HOPS); general population data are estimated from Surveillance, Epidemiology, and End Results (SEER) program data.

    Summary for Patients

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