Meta-analysis: Effect of Monotherapy and Combination Therapy with Inhibitors of the Renin–Angiotensin System on Proteinuria in Renal Disease

  1. Regina Kunz, MD, MSc(Epi);
  2. Chris Friedrich, MD;
  3. Marcel Wolbers, PhD; and
  4. Johannes F.E. Mann, MD
  1. From Basel Institute for Clinical Epidemiology and Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland, and Munich General Hospitals, Ludwig Maximilian University, Munich, Germany.
    1. Appendix Figure 1.
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      Appendix Figure 1. Study flow diagram.Graphic
    2. Appendix Figure 2.
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      Appendix Figure 2. Quality assessment.

      ACE = angiotensin-converting enzyme; ARB = angiotensin-receptor blocker; CCB = calcium-channel blocker; Combi = combination therapy.

    3. Figure 1.
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      Figure 1. Reduction in proteinuria at 1 to 4 months.

      ACE = angiotensin-converting enzyme; ARB = angiotensin-receptor blocker.

    4. Figure 2.
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      Figure 2. Reduction in proteinuria at 5 to 12 months.

      ACE = angiotensin-converting enzyme; ARB = angiotensin-receptor blocker.

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