Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration

  1. Jan P. Vandenbroucke, MD;
  2. Erik von Elm, MD;
  3. Douglas G. Altman, DSc;
  4. Peter C. Gøtzsche, MD;
  5. Cynthia D. Mulrow, MD;
  6. Stuart J. Pocock, PhD;
  7. Charles Poole, ScD;
  8. James J. Schlesselman, PhD;
  9. Matthias Egger, MD; and
  10. for the STROBE initiative
  1. From Leiden University Medical Center, Leiden, the Netherlands; Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland; University Medical Centre, Freiburg, Germany; Cancer Research UK/NHS Centre for Statistics in Medicine, Oxford, United Kingdom; Nordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark; University of Texas Health Science Center, San Antonio, Texas; London School of Hygiene and Tropical Medicine, London, United Kingdom; University of North Carolina School of Public Health, Chapel Hill, North Carolina; University of Pittsburgh Graduate School of Public Health and University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania; and University of Bristol, Bristol, United Kingdom.
    1. Box 1.
      View larger version:
        Box 1. Main Study Designs Covered by STROBE
      • Box 2.
        View larger version:
          Box 2. Matching in Case–Control Studies
        • Box 4.
          View larger version:
            Box 4. Grouping
          • Box 3.
            View larger version:
              Box 3. Bias
            • Box 5.
              View larger version:
                Box 5. Confounding
              • Box 8.
                View larger version:
                  Box 8. Interaction (Effect Modification): The Analysis of Joint Effects
                • Box 6.
                  View larger version:
                    Box 6. Missing Data: Problems and Possible Solutions
                  • Figure.
                    View larger version:
                      Figure. Example of a flow diagram.

                      From reference 141.

                    • Box 7.
                      View larger version:
                        Box 7. Measures of Association, Effect, and Impact
                      « Previous | Next Article »Table of Contents