Anticoagulant Prophylaxis for Hospitalized Medical Patients
- Frank A. Lederle, MD;
- Roderick MacDonald, MS; and
- Timothy J. Wilt, MD, MPH
- From the Minneapolis Veterans Affairs Center for Chronic Disease Outcomes Research, Minneapolis, MN 55417.
TO THE EDITOR:
In their article on anticoagulant prophylaxis to prevent symptomatic venous thromboembolism (VTE) in hospitalized medical patients, Dentali and colleagues (1) base their conclusion that anticoagulant prophylaxis is effective on 2 overlapping significant findings, namely reductions in any pulmonary embolisms (PEs) and fatal PEs. These 2 differences were largely driven by the results of 3 studies: Cohen and colleagues' study (2), Gårdlund's study (3), and Mahé and colleagues' study (4). The devil is in the details, and closer examination of these data calls …
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