Intensive Intraoperative Insulin Therapy versus Conventional Glucose Management during Cardiac Surgery
- Gunjan Y. Gandhi, MD, MSc;
- Gregory A. Nuttall, MD; and
- Martin D. Abel, MD
- From the Mayo Clinic College of Medicine, Rochester, MN 55905.
IN RESPONSE:
Drs. Carvalho and Schricker ask for several details on the surgical interventions pertaining to the applicability of study findings to other settings rather than to the validity of results. It is important to realize that the degree of intraoperative glycemic control was the only difference in study intervention between the 2 groups. The beauty of randomization with allocation concealment is that all known and unknown prognostic variables should be equally distributed between the 2 study groups. Specific surgical details can be provided by personal communication but are …
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