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Benzodiazepines and Hip Fractures
- Anita K. Wagner, PharmD, MPH, DrPH;
- Dennis Ross-Degnan, ScD;
- Stephen B. Soumerai, ScD; and
- Jerry H. Gurwitz, MD
- From Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, and Meyers Primary Care Institute, University of Massachusetts Medical School, Fallon Foundation, and Fallon Community Health Plan, Worcester, MA 01605.
IN RESPONSE:
Dr. Lesser supports our conclusion of the possible lack of a relationship between the use of benzodiazepines and hip fractures in the elderly with additional data from the published literature. Since the landmark studies of 1987 (1) and 1989 (2), results of research on the benzodiazepine–hip fracture relationship have become increasingly contradictory. We concur with Dr. Lesser that differences in results are probably due to study design issues, such as benzodiazepine exposure misclassification …
