Alternative Treatments of Vasomotor Symptoms of Menopause

  1. Baoming Ge, MD, MClSc
  1. From China Clinical Trial Coordination Center, Beijing 100025, China.

    TO THE EDITOR:

    I read the paper on Newton and colleagues' excellent work (1) with great interest. My study group has just finished a pilot study of a black cohosh ethanol extract in Beijing, China, and we are on track to conduct a nationwide, multicenter, randomized, controlled trial. The double-blind pilot study enrolled 120 Chinese women with climacteric symptoms who were stratified into perimenopausal and postmenopausal groups, according to the standard of STRAW (Stages of Reproductive Aging Workshop). We divided each group into 3 intervention groups—low-dose black cohosh (1 pill twice daily), high-dose black cohosh (1 pill thrice daily), and placebo—with 20 persons in each group. The primary outcome was the Kupperman index score, evaluated before the study and at …

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    1. Ann Intern Med September 4, 2007 vol. 147 no. 5 346
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