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Chondroitin for Osteoarthritis of the Knee or Hip
- From the University of Montreal, Osteoarthritis Research Unit, Notre-Dame Hospital, University of Montreal Hospital Centre, Montreal, Quebec H2L 4M1, Canada.
TO THE EDITOR:
The recent meta-analysis on chondroitin sulfate by Reichenbach and colleagues (1) raises many issues related to clinical trials on osteoarthritis. The authors acknowledge that the studies reported in their review are highly heterogeneous in quality, which obviously imposes serious uncertainties to the accuracy of the conclusions drawn. This drawback plagues other meta-analyses in the same field.
With regard to the evaluation of the effect of chondroitin sulfate on osteoarthritis symptoms, the review brings up the issue of …
