Lack of Evidence for Recommended Low-Density Lipoprotein Cholesterol Treatment Targets

  1. Geoffrey A. Modest, MD
  1. From Boston University School of Medicine, Boston, Massachusetts.

    TO THE EDITOR:

    Although Hayward and colleagues' narrative review (1) on treatment targets for low-density lipoprotein (LDL) cholesterol levels raises several important issues, one glaring omission in the relevant studies is that high-density lipoprotein (HDL) cholesterol values are not incorporated into the model. Many clinical studies have found that the relationship between LDL …

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