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Reanalysis of Survival of Oscar Winners
- Donald A. Redelmeier, MD; and
- Sheldon M. Singh, BSc
- From Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5, Canada.
TO THE EDITOR:
In this issue, Sylvestre and colleagues (1) correctly comment that survival statistics are fallible. The primary analysis in our study (2) was based on the Kaplan–Meier method because life expectancy is the preferred metric in medical decision analysis (3). Our article also provided 40 other secondary analyses to explore different models because no one statistic is ideal. Sylvestre and colleagues argue that the multivariate-adjusted Cox proportional hazards model with a time-varying step function is preferred over our primary analysis approach, do not discuss the limitations of such models, and intimate that other models give an unfair advantage. This …
