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The Efficacy and Safety of Multivitamin and Mineral Supplement Use To Prevent Cancer and Chronic Disease in Adults: A Systematic Review for a National Institutes of Health State-of-the-Science Conference
- Han-Yao Huang, PhD, MPH;
- Benjamin Caballero, MD, PhD;
- Stephanie Chang, MD;
- Anthony J. Alberg, PhD, MPH;
- Richard D. Semba, MD, MPH;
- Christine R. Schneyer, MD;
- Renee F. Wilson, MSc;
- Ting-Yuan Cheng, MSc;
- Jason Vassy, MPH;
- Gregory Prokopowicz, MD, MPH;
- George J. Barnes II, BA; and
- Eric B. Bass, MD, MPH
- From the Bloomberg School of Public Health and the School of Medicine, Johns Hopkins University, Baltimore, Maryland.
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Figure 1. Relative risk for cancer with use of multivitamin and mineral supplements.The lines represent 95% CIs, the midpoints of the lines represent the relative risk estimates, and the size of the boxes represents the relative size of the study sample. SU.VI.MAX = SUpplémentation en VItamines et Minéraux AntioXydants. *Vitamin E + selenium + β-carotene + zinc + vitamin C. † Vitamin E + selenium + β-carotene.
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Figure 2. Relative risk for all-cause mortality with use of multivitamin and mineral supplements.The lines represent 95% CIs, the midpoints of the lines represent the relative risk estimates, and the size of the boxes represents the relative size of the study sample. AREDS = Age-Related Eye Disease Study; SU.VI.MAX = SUpplémentation en VItamines et Minéraux AntioXydants. *Vitamin E + selenium + β-carotene + zinc + vitamin C. † Vitamin E + selenium + β-carotene. ‡ Vitamin E + vitamin C + β-carotene.
