Meta-Analysis: The Effect of Statins on Albuminuria
- Kevin Douglas, MD;
- Patrick G. O'Malley, MD, MPH; and
- Jeffrey L. Jackson, MD, MPH
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From Walter Reed Army Medical Center, Washington, DC, and Uniformed Services University of the Health Sciences, Bethesda,
Maryland.
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Figure 1. RCT = randomized, controlled trial. Study flow diagram.
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Figure 2. Residual statistical heterogeneity: I = 23% ( = 0.27) for excretion < 30 mg/d; I = 0% ( = 0.64) for excretion
of 30 to 299 mg/d; and I = 63% ( = 0.020) for excretion ≥ 300 mg/d. WMD = weighted mean difference in the proportional
change from baseline to follow-up albuminuria (or proteinuria) between statin and placebo groups. Individual and pooled results of 15 randomized, placebo-controlled trials examining the effect of statins on albuminuria or
proteinuria, stratified by baseline excretion.2P2P2P
Responses to this article
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Ann Intern Med
July 18, 2006
vol. 145
no. 2
117-124
RSS Feeds
Figure 1. RCT = randomized, controlled trial. Study flow diagram.
Figure 2. Residual statistical heterogeneity: I = 23% ( = 0.27) for excretion < 30 mg/d; I = 0% ( = 0.64) for excretion of 30 to 299 mg/d; and I = 63% ( = 0.020) for excretion ≥ 300 mg/d. WMD = weighted mean difference in the proportional change from baseline to follow-up albuminuria (or proteinuria) between statin and placebo groups. Individual and pooled results of 15 randomized, placebo-controlled trials examining the effect of statins on albuminuria or proteinuria, stratified by baseline excretion.2P2P2P
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