Bisphosphonates and Osteonecrosis of the Jaw
- Sook-Bin Woo, DMD;
- John W. Hellstein, DDS, MS; and
- John R. Kalmar, DMD, PhD
- From Brigham and Women's Hospital and Harvard School of Dental Medicine, Boston, Massachusetts; University of Iowa College of Dentistry, Iowa City, Iowa; and The Ohio State University College of Dentistry, Columbus, Ohio.
IN RESPONSE:
We agree with Drs. Grey and Cundy that no data exist on the incidence or prevalence of osteonecrosis of the jaw in patients taking oral bisphosphonates for osteoporosis. However, the lack of reported cases in the 20 000 patients does not mean that none occurred. Patients who develop what they perceive to be oral or dental problems generally seek help from their dentist or oral surgeon and may not have thought to report the problems to their physician. Furthermore, since the risk for osteonecrosis of the jaw seems to be …
This 100-word excerpt has been provided in the absence of an abstract.
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