Time to Sputum Culture Conversion in Multidrug-Resistant Tuberculosis: Predictors and Relationship to Treatment Outcome
- Timothy H. Holtz, MD, MPH;
- Maya Sternberg, PhD;
- Steve Kammerer, MBA;
- Kayla F. Laserson, ScD;
- Vija Riekstina, MD;
- Evija Zarovska, MD;
- Vija Skripconoka, MD;
- Charles D. Wells, MD; and
- Vaira Leimane, MD
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From Centers for Disease Control and Prevention, Atlanta, Georgia, and the State Agency of Tuberculosis and Lung Diseases,
Riga, Latvia.
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Figure 1. Comparison of γ distribution survival plot versus the observed Kaplan–Meier survival curve in 167 patients.
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Appendix Figure. Comparison of γ, log-normal, and Weibull distribution survival plots versus the observed Kaplan–Meier survival curve in 167
patients.
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Figure 2. Thirty-eight of 167 patients who were sputum culture–positive at treatment initiation did not have conversion. Initial sputum culture conversion in 129 of 167 culture-positive patients who had culture conversion.
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Figure 3. The value reflects the results of the log-rank test of the equality of the 3 survival curves. TB = tuberculosis. Kaplan–Meier survival curve of time to initial sputum culture conversion versus category of previous treatment in 167 patients.P
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Ann Intern Med
May 2, 2006
vol. 144
no. 9
650-659