Time to Sputum Culture Conversion in Multidrug-Resistant Tuberculosis: Predictors and Relationship to Treatment Outcome

  1. Timothy H. Holtz, MD, MPH;
  2. Maya Sternberg, PhD;
  3. Steve Kammerer, MBA;
  4. Kayla F. Laserson, ScD;
  5. Vija Riekstina, MD;
  6. Evija Zarovska, MD;
  7. Vija Skripconoka, MD;
  8. Charles D. Wells, MD; and
  9. Vaira Leimane, MD
  1. From Centers for Disease Control and Prevention, Atlanta, Georgia, and the State Agency of Tuberculosis and Lung Diseases, Riga, Latvia.
    1. Figure 1.
      View larger version:
      Figure 1. Comparison of γ distribution survival plot versus the observed Kaplan–Meier survival curve in 167 patients.
    2. Appendix Figure.
      View larger version:
      Appendix Figure. Comparison of γ, log-normal, and Weibull distribution survival plots versus the observed Kaplan–Meier survival curve in 167 patients.
    3. Figure 2. Thirty-eight of 167 patients who were sputum culture–positive at treatment initiation did not have conversion.
      View larger version:
      Figure 2. Thirty-eight of 167 patients who were sputum culture–positive at treatment initiation did not have conversion. Initial sputum culture conversion in 129 of 167 culture-positive patients who had culture conversion.
    4. Figure 3. The value reflects the results of the log-rank test of the equality of the 3 survival curves. TB = tuberculosis.
      View larger version:
      Figure 3. The value reflects the results of the log-rank test of the equality of the 3 survival curves. TB = tuberculosis. Kaplan–Meier survival curve of time to initial sputum culture conversion versus category of previous treatment in 167 patients.P

    Summary for Patients

    « Previous | Next Article »Table of Contents