Meta-Analysis: Effect of Long-Acting β-Agonists on Severe Asthma Exacerbations and Asthma-Related Deaths

  1. Shelley R. Salpeter, MD;
  2. Nicholas S. Buckley;
  3. Thomas M. Ormiston, MD; and
  4. Edwin E. Salpeter, PhD
  1. From Santa Clara Valley Medical Center, San Jose, California, and Cornell University, Ithaca, New York.
    1. Figure 1.
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        Figure 1. Study flow diagram.
      • Figure 2.
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          Figure 2. Effect of long-acting β-agonists compared with placebo on odds ratio of hospitalizations for asthma exacerbation.
        • Figure 3. SMART = Salmeterol Multi-center Asthma Research Trial.
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            Figure 3. SMART = Salmeterol Multi-center Asthma Research Trial. Effect of long-acting β-agonists compared with placebo on odds ratio of life-threatening asthma exacerbations.

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