Meta-Analysis: Obesity and the Risk for Gastroesophageal Reflux Disease and Its Complications

Appendix Figure 1. Normal weight is defined as a body mass index (BMI) less than 25 kg/m for all studies, except for the study
by Locke and colleagues (BMI < 24 kg/m ) . Overweight is defined as a BMI of 25 kg/m to 30 kg/m for all studies, except for
Locke and colleagues' study (BMI, 24 to 30 kg/m ) and Wu and colleagues' study (BMI, 25 kg/m to 28 kg/m ) . Obese is defined
as a BMI greater than 30 kg/m for all studies, except Wu and colleagues' study (BMI > 28 kg/m ) . Pooled weighted odds ratios
are also given for overweight and obesity (that is, BMI ≥ 25 kg/m compared with BMI < 25 kg/m ).
Unadjusted odds ratios (95% CIs) for the risk for gastroesophageal reflux disease (GERD) symptoms among overweight (top) and
obese (bottom) versus normal-weight individuals.22(23)222(23)22(27)22(27)22
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Ann Intern Med
August 2, 2005
vol. 143
no. 3
199-211