Meta-Analysis: The Value of Clinical Assessment in the Diagnosis of Deep Venous Thrombosis
- Steve Goodacre, MB, ChB, FFAEM, MSc, PhD;
- Alex J. Sutton, BSc, MSc, PhD; and
- Fiona C. Sampson, BA, MSc
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From University of Sheffield, Sheffield, and University of Leicester, Leicester, United Kingdom.
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Figure 1. *κ = 0.85. †κ = 0.86. Flow diagram of studies considered for the review.
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Figure 2. Meta-analysis estimates of diagnostic value of clinical features of deep venous thrombosis (DVT).
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Figure 3. Post-test probability of deep venous thrombosis after high or low Wells scores as a function of pretest probability (population
prevalence of deep venous thrombosis).
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Figure 4. Two results are plotted from each study of the Wells score on the receiver-operating characteristic plane. Circles
represent use of a high versus intermediate and low decision threshold (that is, only persons categorized as at high risk
receive a diagnosis of deep venous thrombosis). Triangles represent a high and intermediate versus low decision threshold
(that is, persons categorized as at high or intermediate risk receive a diagnosis of deep venous thrombosis). The point estimates
and 95% CIs for pooled sensitivity and specificity for the 2 thresholds are also plotted as boxes. Performance of the Wells clinical risk score for detecting all episodes of deep venous thrombosis.
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Ann Intern Med
July 19, 2005
vol. 143
no. 2
129-139
RSS Feeds
Figure 1. *κ = 0.85. †κ = 0.86. Flow diagram of studies considered for the review.
Figure 2. Meta-analysis estimates of diagnostic value of clinical features of deep venous thrombosis (DVT).
Figure 3. Post-test probability of deep venous thrombosis after high or low Wells scores as a function of pretest probability (population prevalence of deep venous thrombosis).
Figure 4. Two results are plotted from each study of the Wells score on the receiver-operating characteristic plane. Circles represent use of a high versus intermediate and low decision threshold (that is, only persons categorized as at high risk receive a diagnosis of deep venous thrombosis). Triangles represent a high and intermediate versus low decision threshold (that is, persons categorized as at high or intermediate risk receive a diagnosis of deep venous thrombosis). The point estimates and 95% CIs for pooled sensitivity and specificity for the 2 thresholds are also plotted as boxes. Performance of the Wells clinical risk score for detecting all episodes of deep venous thrombosis.
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