Tumor Necrosis Factor-α Inhibitor Therapy in Erosive Polyarthritis Secondary to Systemic Sclerosis

  1. Silvia Bosello, MD;
  2. Maria De Santis, MD;
  3. Barbara Tolusso, BS;
  4. Angelo Zoli, MD; and
  5. Gianfranco Ferraccioli, MD
  1. From the Catholic University of the Sacred Heart, 00168 Rome, Italy.

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    TO THE EDITOR:

    Background: Inflammatory arthritis can occur in patients with systemic sclerosis. In some cases, the condition is erosive and the patient is rheumatoid factor–seronegative, whereas some patients have rheumatoid arthritis that overlaps with diffuse (1) or limited (2) systemic sclerosis. Symptoms may not respond to corticosteroid or methotrexate therapy.

    Objective: To …

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