Table of Contents

November 15, 2005; 143 (10)

Articles

  • Trends in the Incidence of Venous Thromboembolism during Pregnancy or Postpartum: A 30-Year Population-Based Study

    • John A. Heit,
    • Catie E. Kobbervig,
    • Andra H. James,
    • Tanya M. Petterson,
    • Kent R. Bailey,
    • and L. Joseph Melton III
    Ann Intern Med November 15, 2005 143:697-706

    The incidence of venous thromboembolism during pregnancy has remained constant in the past 30 years. While the incidence of pulmonary embolism has been much higher in the postpartum period, it has decreased sharply in the past decade. Women younger than age 20 years and older than age 35 years are at greatest risk. The benefits and harms of prophylaxis with anticoagulants are not known in these patients.

  • The Relationship between Condom Use and Herpes Simplex Virus Acquisition

    • Anna Wald,
    • Andria G.M. Langenberg,
    • Elizabeth Krantz,
    • John M. Douglas, Jr,
    • H. Hunter Handsfield,
    • Richard P. DiCarlo,
    • Adaora A. Adimora,
    • Allen E. Izu,
    • Rhoda Ashley Morrow,
    • and Lawrence Corey
    Ann Intern Med November 15, 2005 143:707-713

    The authors evaluated the relationship between condom use and acquisition of herpes simplex virus (HSV)-2 and HSV-1. In this observational study, consistent use of condoms was associated with lower rates of acquisition of HSV-2. Reducing the risk for HSV-2 acquisition is another reason for people at high risk for sexually transmitted disease to use condoms.

  • Impact of Efavirenz on Neuropsychological Performance and Symptoms in HIV-Infected Individuals

    • David B. Clifford,
    • Scott Evans,
    • Yijun Yang,
    • Edward P. Acosta,
    • Karl Goodkin,
    • Karen Tashima,
    • David Simpson,
    • David Dorfman,
    • Heather Ribaudo,
    • Roy M. Gulick,
    • and for the A5097s Study Team*
    Ann Intern Med November 15, 2005 143:714-721

    Highly active antiretroviral therapy (HAART) regimens often include efavirenz. Physicians caring for HIV-infected patients have attributed adverse neuropsychological effects to efavirenz. In this substudy of a randomized trial, patients taking efavirenz had more neurologic symptoms during week 1 of treatment than patients taking placebo, but the rates were similar at weeks 4, 12, or 24.

  • The Metabolic Syndrome as a Predictor of Nonalcoholic Fatty Liver Disease

    • Masahide Hamaguchi,
    • Takao Kojima,
    • Noriyuki Takeda,
    • Takayuki Nakagawa,
    • Hiroya Taniguchi,
    • Kota Fujii,
    • Tatsushi Omatsu,
    • Tomoaki Nakajima,
    • Hiroshi Sarui,
    • Makoto Shimazaki,
    • Takahiro Kato,
    • Junichi Okuda,
    • and Kazunori Ida
    Ann Intern Med November 15, 2005 143:722-728

    The authors examined the role of the metabolic syndrome in the development of nonalcoholic fatty liver disease (NAFLD) in 4401 Japanese men and women. At baseline, 812 of participants had NAFLD. During follow-up, NAFLD developed in 10% of 3147 participants who were free of NAFLD at baseline. Having the metabolic syndrome at baseline was a strong predictor of developing NAFLD.

Improving Patient Care

  • Quality of HIV Care Provided by Nurse Practitioners, Physician Assistants, and Physicians

    • Ira B. Wilson,
    • Bruce E. Landon,
    • Lisa R. Hirschhorn,
    • Keith McInnes,
    • Lin Ding,
    • Peter V. Marsden,
    • and Paul D. Cleary
    Ann Intern Med November 15, 2005 143:729-736

    According to 8 quality-of-care measures assessed by medical record review, the quality of HIV care by nurse practitioners and physician assistants was similar to that provided by physician HIV care experts and was generally better than that provided by physicians who were not HIV care experts.

Updates

  • Update in Cardiology

    • Peter H. Stone
    Ann Intern Med November 15, 2005 143:737-743

    This Update covers the highlights of an extraordinary year in cardiology, including important research in the areas of unstable and stable coronary artery syndromes, risk factors for atherosclerotic disease, heart failure, cardiomyopathy, arrhythmias, peripheral vascular disease, and valvular heart disease.

Perspectives

  • The Terri Schiavo Case: Legal, Ethical, and Medical Perspectives

    • Joshua E. Perry,
    • Larry R. Churchill,
    • and Howard S. Kirshner
    Ann Intern Med November 15, 2005 143:744-748

    The conflicts and misunderstandings surrounding the plight of Terri Schiavo offer important lessons in medicine, law, and ethics. The authors review the current medical understanding of the persistent vegetative state, examine the legal history of the case, and review alternative ethical frameworks for thinking about the case.

Editorials

  • Thromboembolism in Pregnancy: A Continuing Conundrum

    • Richard V. Lee
    Ann Intern Med November 15, 2005 143:749-750

    In this issue, Heit and colleagues provide solid clinical evidence to confirm current clinical wisdom: Pregnancy increases the risk for thromboembolism. No time during pregnancy is without thromboembolic risk.

  • An Ounce of Prevention

    • Edward W. Hook III
    Ann Intern Med November 15, 2005 143:751-752

    In this issue, Wald and coworkers have further expanded the menu of proven measures for prevention of herpesvirus transmission, demonstrating that condoms protected men from genital herpes in a dose-dependent fashion. Strengths of the study include its multicenter design, the large number of carefully evaluated participants, and use of serologic measures for detection of infection.

  • Dangerous Liaisons: The Metabolic Syndrome and Nonalcoholic Fatty Liver Disease

    • Elizabeth E. Powell,
    • Julie R. Jonsson,
    • and Andrew D. Clouston
    Ann Intern Med November 15, 2005 143:753-754

    In this issue, Hamaguchi and colleagues examined the relationship between the metabolic syndrome and nonalcoholic fatty liver disease (NAFLD) in healthy Japanese men and women drinking less than 20 g of ethanol per day. By identifying both prevalent and incident cases, the authors provide important new data on the rate of development or regression of NAFLD.

On Being a Doctor

  • Looking for Betty

    • Jaime E. Ollé-Goig
    Ann Intern Med November 15, 2005 143:755

    The laboratory results suggest tuberculosis. I start Betty immediately on antituberculosis medications through a nasogastric tube and streptomycin injections. Three days later, her temperature has dropped and she has begun to talk in a lively manner. On the morning of the fifth day, Betty is no longer in her bed. The nurses think that she was probably taken away during the night.

Letters

  • Preventing Sudden Cardiac Death

    • Michael Achtelik
    Ann Intern Med November 15, 2005 143:756

  • Preventing Sudden Cardiac Death

    • Stephen G. Pauker,
    • N. A. Mark Estes,
    • and Deeb N. Salem
    Ann Intern Med November 15, 2005 143:756

  • Advanced Lipoprotein Testing in Young Adults

    • Paul Ziajka
    Ann Intern Med November 15, 2005 143:756-757

  • Advanced Lipoprotein Testing in Young Adults

    • Wendy S. Tzou and
    • James H. Stein
    Ann Intern Med November 15, 2005 143:757

  • Cost-Effectiveness in Hepatitis B

    • Gil Weitzman and
    • Ira Jacobson
    Ann Intern Med November 15, 2005 143:757-758

  • Cost-Effectiveness in Hepatitis B

    • Brennan M.R. Spiegel,
    • Paul Martin,
    • and Fasiha Kanwal
    Ann Intern Med November 15, 2005 143:758-759

  • Outlier Status of U.S. Health Care Costs

    • Michael J. Keberlein
    Ann Intern Med November 15, 2005 143:759

  • Outlier Status of U.S. Health Care Costs

    • Steven D. Hanks
    Ann Intern Med November 15, 2005 143:759

  • Outlier Status of U.S. Health Care Costs

    • Thomas Bodenheimer
    Ann Intern Med November 15, 2005 143:760

  • The New York Case: Lessons Being Learned

    • Thomas R. Frieden
    Ann Intern Med November 15, 2005 143:760

  • Patient-to-Patient Transmission of Hepatitis C

    • Michel Y. Jadoul
    Ann Intern Med November 15, 2005 143:761

  • Immune Thrombocytopenia Associated with Efalizumab Therapy for Psoriasis

    • Theodore E. Warkentin and
    • Paul Kwon
    Ann Intern Med November 15, 2005 143:761-763

  • Bradycardia and Edema in a Patient Receiving Herbal Therapy for Fertility

    • Rana Adawi and
    • Liron Walsh
    Ann Intern Med November 15, 2005 143:763

  • Sibutramine Use Associated with Reversible Hepatotoxicity

    • Athina Chounta,
    • Sotirios Tsiodras,
    • Spyros Zouridakis,
    • Michalis Doumas,
    • and Helen Giamarellou
    Ann Intern Med November 15, 2005 143:763-764

  • Correction: Single-Therapy Androgen Suppression in Men with Advanced Prostate Cancer: A Systematic Review and Meta-Analysis

    Ann Intern Med November 15, 2005 143:764-765

  • Correction: Meeting Transfusion Safety Expectations

    Ann Intern Med November 15, 2005 143:765

Medical Writings: Book Notes

  • Evidence-Based Medicine and the Search for a Science of Clinical Care

    • John M. Byrne
    Ann Intern Med November 15, 2005 143:772

  • Aging Men's Health: A Case-Based Approach

    • Lisa B. Caruso and
    • Ricardo Munarriz
    Ann Intern Med November 15, 2005 143:772

Medical Writings: Words That Make a Difference

  • “What Else?” Setting the Agenda for the Clinical Interview

    • Laurence H. Baker,
    • Daniel O'Connell,
    • and Frederic W. Platt
    Ann Intern Med November 15, 2005 143:766-770

    Because patients often have multiple symptoms, physicians must define an agenda for every medical encounter. Key tasks include discovering the patient's and the clinician's most urgent issues and deciding together which issues to address first.

Current Clinical Issues

  • Why Prion Diseases Are a Mystery, and Why They Matter

    • Jennifer Fisher Wilson
    Ann Intern Med November 15, 2005 143:773-776

Ad Libitum

Medical Notices

  • Medical Notices

    Ann Intern Med November 15, 2005 143:0

Summaries for Patients

  • Evaluating the Risk for Pregnancy-Associated Venous Thromboembolism: A 30-Year Study

    Ann Intern Med November 15, 2005 143:I-12

  • Condom Use and Genital Herpes

    Ann Intern Med November 15, 2005 143:I-40

  • Neuropsychological Side Effects of Efavirenz

    Ann Intern Med November 15, 2005 143:I-43

  • The Metabolic Syndrome and Fatty Liver Disease

    Ann Intern Med November 15, 2005 143:I-70

  • Quality of HIV Health Care Provided by Nurse Practitioners, Physician Assistants, and Doctors

    Ann Intern Med November 15, 2005 143:I-72
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This Issue

November 15, 2005; 143 (10)
  1. Articles
  2. Improving Patient Care
  3. Updates
  4. Perspectives
  5. Editorials
  6. On Being a Doctor
  7. Letters
  8. Medical Writings: Book Notes
  9. Medical Writings: Words That Make a Difference
  10. Current Clinical Issues
  11. Ad Libitum
  12. Medical Notices
  13. Summaries for Patients

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