Effect of Soybean Protein on Blood Pressure: A Randomized, Controlled Trial
- Jiang He, MD, PhD;
- Dongfeng Gu, MD, MS;
- Xigui Wu, MD;
- Jichun Chen, MSc;
- Xiufang Duan, MD;
- Jing Chen, MD, MSc; and
- Paul K. Whelton, MD, MSc
- From Tulane University, New Orleans, Louisiana; and Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College, Beijing, People's Republic of China.
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Figure 1. BP = blood pressure. Study participant flow chart. -
Figure 2. The mean systolic and diastolic blood pressures are shown for the soybean protein supplementation and complex carbohydrate control groups at the baseline, 6-week, and 12-week visits. The numbers next to the dotted lines are the mean differences (95% CIs) in blood pressure change from baseline to 6-week and 12-week visits between the soybean protein supplementation group and the complex carbohydrate control group. Data presented are from the 281 trial participants at week 6 and the 276 trial participants at week 12 who completed the intervention. The effect of soybean protein supplementation on systolic (top) and diastolic (bottom) blood pressure. -
Figure 3. The mean difference and 95% CIs are shown for change in blood pressure from the baseline to 12-week visits between the soybean protein supplementation group and the complex carbohydrate control group. Overweight was defined as a body mass index ≥25 kg/m , and hypertension was defined as systolic blood pressure ≥140 mm Hg, diastolic blood pressure ≥90 mm Hg, or both. Error bars represent 95% CIs. values are for interaction between a characteristic and the blood pressure effect of soybean protein. The effect of soybean protein supplementation on systolic (top) and diastolic (bottom) blood pressure according to subgroup.2P
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