Review: Recommendations for the Diagnosis and Treatment of the Acute Porphyrias
  • Karl E. Anderson,
  • Joseph R. Bloomer,
  • Herbert L. Bonkovsky,
  • James P. Kushner,
  • Claus A. Pierach,
  • Neville R. Pimstone,
  • and Robert J. Desnick
Ann Intern Med March 15, 2005 142:439-450

  1. Exacerbation of Acute intermittent porphyria by substance abuse

    • Ajit S Kashyap, MD
    • Kuldip P Anand, Surekha Kashyap, and Abhijeet Anand
    Department of Endocrinology,Command Hospital (Southern Command),Pune 411 040,India

    In their excellent review on porphyria Anderson et al (1) fail to mention substance abuse, particularly marijuana, ecstasy, amphetamines, and cocaine as an important precipitants of acute exacerbations of acute intermittent porphyria. (2,3) References 1. Anderson KE, Bloomer JR, Bonkovsky HL, et al. Recommendations for the diagnosis and treatment of the acute porphyries 2. Thadani H, Deacon A. Diagnosis and management of Porphyrias. BMJ 2000;320:1647-1651. 3 Lip GY, McColl KE, Goldberg A, Moore MR. Smoking and recurrent attacks of acute intermittent porphyria BMJ. 1991 Mar 2;302(6775):507.

    Conflict of Interest:

    None declared

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    Published April 14, 2005
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