Challenges in Using Nonrandomized Studies in Systematic Reviews of Treatment Interventions

  1. Susan L. Norris, MD, MPH; and
  2. David Atkins, MD, MPH
  1. From the Agency for Healthcare Research and Quality, Rockville, Maryland.
    1. Figure 1. RCT = randomized, controlled trial.
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      Figure 1. RCT = randomized, controlled trial. Study designs used in Evidence-based Practice Center reports.
    2. Figure 2. Included are reports that examined 1 or more questions of clinical effectiveness (  = 49). Bars represent the number of reports that included the specific study design. Totals exceed 49 because each report can include more than 1 clinical question and more than 1 study design.
      View larger version:
      Figure 2. Included are reports that examined 1 or more questions of clinical effectiveness (  = 49). Bars represent the number of reports that included the specific study design. Totals exceed 49 because each report can include more than 1 clinical question and more than 1 study design. Study designs by type of clinical question for Evidence-based Practice Center reports.n
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    1. Ann Intern Med June 21, 2005 vol. 142 no. 12 Part 2 1112-1119
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