Benefits and Harms of Doxycycline Treatment for Gulf War Veterans' Illnesses
- Sam T. Donta, MD;
- Charles C. Engel, Jr., MD, MPH;
- Joseph F. Collins, ScD;
- Joel B. Baseman, PhD;
- Lisa L. Dever, MD;
- Thomas Taylor, MD;
- Kathy D. Boardman, RPh;
- Lewis E. Kazis, ScD;
- Suzanne E. Martin;
- Rebecca A. Horney, BS;
- Annette L. Wiseman;
- Douglas S. Kernodle, MD;
- Raymond P. Smith, MD;
- Aldona L. Baltch, MD;
- Christine Handanos, MD;
- Brian Catto, MD;
- Luis Montalvo, MD;
- Michael Everson, PhD;
- Warren Blackburn, MD;
- Manisha Thakore, MD;
- Sheldon T. Brown, MD;
- Larry Lutwick, MD;
- Dorothy Norwood, MD;
- Jack Bernstein, MD;
- Catherine Bacheller, MD;
- Bruce Ribner, MD;
- L. W. Preston Church, MD;
- Kenneth H. Wilson, MD;
- Prabhakar Guduru, MD;
- Robert Cooper, MD;
- Joseph Lentino, MD;
- Richard J. Hamill, MD;
- Arnold B. Gorin, MD;
- Victor Gordan, MD;
- David Wagner, MD;
- Cliff Robinson, MD;
- Pierre DeJace, MD;
- Ronald Greenfield, MD;
- Lisa Beck, MD;
- Marvin Bittner, MD;
- H. Ralph Schumacher, MD;
- Fredric Silverblatt, MD;
- James Schmitt, MD;
- Edward Wong, MD;
- Margaret A.K. Ryan, MD, MPH;
- Javier Figueroa, MD;
- Christopher Nice, MD;
- John R. Feussner, MD, MPH; and
- the VA Cooperative #475 Group
-
From Veterans Affairs Medical Centers (Boston, Massachusetts; Milwaukee, Wisconsin; Montgomery, Alabama; Perry Point, Maryland;
East Orange, New Jersey; White River Junction, Vermont; Albuquerque, New Mexico; Bedford, Massachusetts; Nashville, Tennessee;
Albany, New York; Augusta, Georgia; Birmingham, Alabama; Bronx, New York; Brooklyn, New York; Dayton, Ohio; Charleston, South
Carolina; Durham, North Carolina; Fargo, North Dakota; Hines, Illinois; Houston, Texas; Manchester, New Hampshire; New Orleans,
Louisiana; Oklahoma City, Oklahoma; Omaha, Nebraska; Philadelphia, Pennsylvania; Providence, Rhode Island; Richmond, Virginia;
and San Juan, Puerto Rico); Uniformed Services University of the Health Sciences, Bethesda, Maryland; University of Texas
Health Science Center, San Antonio, Texas; Naval Health Research Center, San Diego, California; and Department of Veterans
Affairs National Central Office, Washington, DC.
-
Figure 1. *Of these participants, 15 returned for the 12-month visit and had 12-month data for the Physical Component Summary
score, while the remaining 28 were considered to have had treatment failure for the primary outcome measure. †Of these participants,
14 returned for the 12-month visit and had 12-month data for the Physical Component Summary score; treatment was considered
to have failed in the remaining 35. GWVIs = Gulf War veterans' illnesses. Progress of participants through the trial.
-
Figure 2. Error bars represent 95% CIs. Study participants who improved more than 7 units on the Veterans Short Form-36 Health Survey Physical Component Summary score
at each rating period compared with baseline.
Responses to this article
-
Ann Intern Med
July 20, 2004
vol. 141
no. 2
85-94
RSS Feeds
View larger version:Figure 1. *Of these participants, 15 returned for the 12-month visit and had 12-month data for the Physical Component Summary score, while the remaining 28 were considered to have had treatment failure for the primary outcome measure. †Of these participants, 14 returned for the 12-month visit and had 12-month data for the Physical Component Summary score; treatment was considered to have failed in the remaining 35. GWVIs = Gulf War veterans' illnesses. Progress of participants through the trial.
View larger version:Figure 2. Error bars represent 95% CIs. Study participants who improved more than 7 units on the Veterans Short Form-36 Health Survey Physical Component Summary score at each rating period compared with baseline.
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