Meta-Analysis: The Effect of Steroids on Survival and Shock during Sepsis Depends on the Dose

Figure 4. The relative benefit (95% CI) and the hazard ratio (with 95% CI) of shock reversal for the sepsis trials published after 1997 are presented. Of note, in 3 of the 4 studies, the discontinuation of vasopressor therapy with steroid treatment statistically significantly improved. In the fourth trial, the effect of steroid therapy on vasopressor discontinuation was similar to the effect in the other trials (I = 0%;  > 0.2).
Figure 4. The relative benefit (95% CI) and the hazard ratio (with 95% CI) of shock reversal for the sepsis trials published after 1997 are presented. Of note, in 3 of the 4 studies, the discontinuation of vasopressor therapy with steroid treatment statistically significantly improved. In the fourth trial, the effect of steroid therapy on vasopressor discontinuation was similar to the effect in the other trials (I = 0%;  > 0.2). Effects of steroids on shock reversal.2P

This Article

  1. Ann Intern Med July 6, 2004 vol. 141 no. 1 47-56
  1. AbstractFREE
  2. Figures
  3. Full Text
  4. Full Text (PDF)

Current Issue

  1. December 1, 2009, 151 (11)
  1. Alert me to current issues