High-Dose and Low-Dose Cosyntropin Stimulation Tests for Diagnosis of Adrenal Insufficiency

  1. Richard I. Dorin, MD;
  2. Clifford R. Qualls, PhD; and
  3. Lawrence M. Crapo, MD, PhD
  1. From New Mexico Veterans Affairs Healthcare System and University of New Mexico School of Medicine, Albuquerque, NM 87108; and Santa Clara Valley Medical Center, San Jose, CA 95128.

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    IN RESPONSE:

    The paper by Gandhi and associates (1) was excluded from our analysis because of inadequate stratification of patients by gold standard testing (only 7 of 31 patients had an insulin tolerance or metyrapone test). The paper by Choi and coworkers (2) appeared on MEDLINE in April 2003, after our final draft was submitted, and includes 72 patients who underwent the 1-µg test and the insulin tolerance test. The paper by Rose and colleagues (3) was not detected …

    This 100-word excerpt has been provided in the absence of an abstract.

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