Table of Contents

February 17, 2004; 140 (4)

Articles

  • Cognitive Impairment and Decline Are Associated with Carotid Artery Disease in Patients without Clinically Evident Cerebrovascular Disease

    • S. Claiborne Johnston,
    • Ellen S. O'Meara,
    • Teri A. Manolio,
    • David Lefkowitz,
    • Daniel H. O'Leary,
    • Steven Goldstein,
    • Michelle C. Carlson,
    • Linda P. Fried,
    • and W. T. Longstreth, Jr.
    Ann Intern Med February 17, 2004 140:237-247

    Cognitive impairment and decline are associated with asymptomatic high-grade stenosis of the left internal carotid artery but not the right carotid artery. The lack of association with right-sided stenosis indicates that the association is specific and not due to generalized atherosclerosis.

  • Retinal Arteriolar Diameter and Risk for Hypertension

    • Tien Yin Wong,
    • Ronald Klein,
    • A. Richey Sharrett,
    • Bruce B. Duncan,
    • David J. Couper,
    • Barbara E.K. Klein,
    • Larry D. Hubbard,
    • F. Javier Nieto,
    • and for the Atherosclerosis Risk in Communities Study
    Ann Intern Med February 17, 2004 140:248-255

    Researchers have speculated that narrowing of the small arterioles contributes to the pathogenesis of hypertension. In this prospective study, patients who were normotensive at baseline but had narrowed retinal arterioles were more likely to develop hypertension later in life. Arteriolar narrowing may be an early stage of hypertension.

  • The Prognostic Importance of Changes in CD4+ Cell Count and HIV-1 RNA Level in Women after Initiating Highly Active Antiretroviral Therapy

    • Kathryn Anastos,
    • Yolanda Barrón,
    • Mardge H. Cohen,
    • Ruth M. Greenblatt,
    • Howard Minkoff,
    • Alexandra Levine,
    • Mary Young,
    • and Stephen J. Gange
    Ann Intern Med February 17, 2004 140:256-264

    The CD4+ cell count and HIV-1 RNA level after highly active antiretroviral therapy predict death and new AIDS-defining illness. Pretreatment values of these markers do not predict clinical outcomes if post-treatment values are taken into account. Highly active antiretroviral therapy can overcome even advanced immunesuppression if treatment results in CD4+ cell counts of greater than 0.200 × 109 cells/L and RNA levels of less than 10 000 copies/mL.

Brief Communications

  • The Natural History of Lone Atrial Flutter

    • Sean C. Halligan,
    • Bernard J. Gersh,
    • Robert D. Brown, Jr.,
    • A. Gabriela Rosales,
    • Thomas M. Munger,
    • Win-Kuang Shen,
    • Stephen C. Hammill,
    • and Paul A. Friedman
    Ann Intern Med February 17, 2004 140:265-268

    Lone atrial flutter has a stroke risk at least as high as lone atrial fibrillation. The risk for atrial fibrillation is higher in patients with lone atrial flutter than in the general population. Physicians should consider long-term anticoagulation for all patients with atrial flutter who are older than 65 years of age.

Improving Patient Care

  • Medicare Program Expenditures Associated with Hospice Use

    • Diane E. Campbell,
    • Joanne Lynn,
    • Tom A. Louis,
    • and Lisa R. Shugarman
    Ann Intern Med February 17, 2004 140:269-277

    Hospice enrollment correlates with slightly lower Medicare expenditures among people dying of cancer, especially lung cancer and other aggressive types of cancer. Medicare expenditures are higher for hospice patients dying of other diseases, such as heart failure and dementia. Overall, Medicare expenditures are higher for dying patients enrolled in hospice than for dying patients who do not enroll in hospice.

Academia and Clinic

  • Evidence-Based Diagnostic Strategies for Evaluating Suspected Allergic Rhinitis

    • Karna Gendo and
    • Eric B. Larson
    Ann Intern Med February 17, 2004 140:278-289

    This paper reviews the use of the history, skin tests, and in vitro tests in diagnosing allergic rhinitis. In patients whose history strongly suggests allergic rhinitis, tests are not helpful except in patients who do not respond to standard treatment and must consider immunotherapy or allergen avoidance. Tests are more likely to change management if the pretest probability of allergic rhinitis is relatively low.

Medicine and Public Issues

  • Medical Device Regulation: An Introduction for the Practicing Physician

    • William H. Maisel
    Ann Intern Med February 17, 2004 140:296-302

    This article describes the rules that govern the approved and unapproved use of medical devices. It also describes the federal government's processes for premarket evaluation and approval and postmarket surveillance of medical devices.

Editorials

  • Carotid Disease and Cognitive Dysfunction

    • H.J.M. Barnett
    Ann Intern Med February 17, 2004 140:303-304

    In this issue, Johnston and colleagues report on cognition at baseline and subsequent cognitive decline in 4006 patients who were free of symptomatic vascular disease. They found an association between stenosis of the carotid artery that supplies the dominant hemisphere and cognitive impairment and decline. Although their evidence is important, we need larger, more inclusive studies before deciding that carotid stenosis causes functionally important cognitive impairment.

  • Starting Highly Active Antiretroviral Therapy for HIV Infection: Is It WIHS To Wait?

    • Robert T. Schooley
    Ann Intern Med February 17, 2004 140:305-306

    In this issue, Anastos and colleagues analyzed the predictors of successful outcomes of antiretroviral chemotherapy in women participating in the Women's Interagency Health Study. Even persons with advanced HIV disease benefited from antiretroviral chemotherapy, and a patient's response to therapy was more predictive of death and AIDS than baseline markers of disease activity.

On Being a Doctor

  • To Be a Doctor in Jerusalem: Life under Threat of Terrorism

    • Yishai Ofran and
    • Shaden Salameh Giryes
    Ann Intern Med February 17, 2004 140:307-308

    In 1948, when the state of Israel was established, Jerusalem was divided between Israel and Jordan. Consequently, Mount Scopus, the location of the Hebrew University campus and Hadassah University hospital, became an Israeli enclave in the midst of an Arab population. This article reflects our daily experience as doctors in Hadassah Mount Scopus Hospital. We are 2 residents, one Jewish, one Arab, working together in the internal medicine ward.

Letters

  • Duration of Antibiotic Therapy for Lyme Disease

    • Raphael B. Stricker and
    • Edward L. McNeil
    Ann Intern Med February 17, 2004 140:W-6

  • Duration of Antibiotic Therapy for Lyme Disease

    • Allen C. Steere
    Ann Intern Med February 17, 2004 140:W-7

  • Dark Rounds

    • David Mullins
    Ann Intern Med February 17, 2004 140:W-8

  • The Symbol of Modern Medicine

    • Michael E. Toedt and
    • Dominique M. Gooby Toedt
    Ann Intern Med February 17, 2004 140:309

  • The Symbol of Modern Medicine

    • Neni Prasad
    Ann Intern Med February 17, 2004 140:309

  • The Symbol of Modern Medicine

    • Adrian G. Letz
    Ann Intern Med February 17, 2004 140:309-310

  • The Symbol of Modern Medicine

    • Drew Hause
    Ann Intern Med February 17, 2004 140:310

  • The Symbol of Modern Medicine

    • Meyer D. Lifschitz
    Ann Intern Med February 17, 2004 140:310

  • The Symbol of Modern Medicine

    • Sarkis J. Chobanian
    Ann Intern Med February 17, 2004 140:310-311

  • The Symbol of Modern Medicine

    • David P. Steensma
    Ann Intern Med February 17, 2004 140:311

  • The Symbol of Modern Medicine

    • Konstantinos Paparounas
    Ann Intern Med February 17, 2004 140:311

  • The Symbol of Modern Medicine

    • Jamie Newman
    Ann Intern Med February 17, 2004 140:311

  • The Symbol of Modern Medicine

    • Robert A. Wilcox and
    • Emma M. Whitham
    Ann Intern Med February 17, 2004 140:311-312

  • High-Dose and Low-Dose Cosyntropin Stimulation Tests for Diagnosis of Adrenal Insufficiency

    • Gabriel Dickstein
    Ann Intern Med February 17, 2004 140:312-313

  • High-Dose and Low-Dose Cosyntropin Stimulation Tests for Diagnosis of Adrenal Insufficiency

    • Richard I. Dorin,
    • Clifford R. Qualls,
    • and Lawrence M. Crapo
    Ann Intern Med February 17, 2004 140:313-314

  • Responsiveness of Thrombotic Thrombocytopenic Purpura to Rituximab and Cyclophosphamide

    • Fadi Fakhouri,
    • Luis Teixeira,
    • Richard Delarue,
    • Jean-Pierre Grünfeld,
    • and Agnès Veyradier
    Ann Intern Med February 17, 2004 140:314-315

  • Correction: Diagnosis of Adrenal Insufficiency

    Ann Intern Med February 17, 2004 140:315

  • Correction: Gatifloxacin-Induced Hepatotoxicity and Acute Pancreatitis

    Ann Intern Med February 17, 2004 140:315

Medical Writings: Book Notes

  • The Requisites in Gastroenterology. Volume 1: Esophagus and Stomach

    • Andrew G. Plaut
    Ann Intern Med February 17, 2004 140:316

  • Iconoclast: Abraham Flexner and a Life in Learning

    • Joel D. Howell
    Ann Intern Med February 17, 2004 140:316

Current Clinical Issues

  • The Promise of Disease Proteomics: Faster Detection, Diagnosis, and Drug Development

    • Jennifer Fisher Wilson
    Ann Intern Med February 17, 2004 140:317-319

Book Listings

  • Book Listings

    Ann Intern Med February 17, 2004 140:0

Medical Notices

  • Medical Notices

    Ann Intern Med February 17, 2004 140:0

Summaries for Patients

  • Cognitive Function and Carotid Artery Disease

    Ann Intern Med February 17, 2004 140:I-34

  • Do Narrowed Blood Vessels Lead to Hypertension?

    Ann Intern Med February 17, 2004 140:I-38

  • The Relationship of Pre- and Post-Treatment Laboratory Tests with Outcomes for Women Starting Treatment for HIV Infection

    Ann Intern Med February 17, 2004 140:I-45

  • Outcomes of Patients with Lone Atrial Flutter

    Ann Intern Med February 17, 2004 140:I-55

Updates from the Annual Session

  • Update in Infectious Diseases

    • Merle A. Sande and
    • Allan R. Ronald
    Ann Intern Med February 17, 2004 140:290-295

    This year's Update in Infectious Diseases focuses on the severe acute respiratory syndrome (SARS), hepatitis B, respiratory viruses, antibiotic resistance, and vaccination. In the past year, we heard both alarming findings about emerging infectious diseases and drug-resistant bacteria and exciting findings about new vaccines and more effective therapy for infectious diseases.

« Previous | Next Issue »

This Issue

February 17, 2004; 140 (4)
  1. Articles
  2. Brief Communications
  3. Improving Patient Care
  4. Academia and Clinic
  5. Medicine and Public Issues
  6. Editorials
  7. On Being a Doctor
  8. Letters
  9. Medical Writings: Book Notes
  10. Current Clinical Issues
  11. Book Listings
  12. Medical Notices
  13. Summaries for Patients
  14. Updates from the Annual Session

Search in this issue:

Current Issue

  1. November 3, 2009, 151 (9)
  1. Alert me to current issues