A Novel Diagnostic Method for Acute Pulmonary Embolism: Technetium-99m Apcitide Scintigraphy

  1. Jonathan M. Davison, MD;
  2. Robert Bridwell, MD, MBA;
  3. Jamie L. Montilla, MD;
  4. Edward Jackson, MD; and
  5. Lisa K. Moores, MD
  1. From Walter Reed Army Medical Center, Washington, DC 20307-5001.

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    Editor's Note:The lead author of the following Clinical Observation was one of a dozen Associates of the American College of Physicians selected to present a clinical vignette at the 2002 Annual Session in Philadelphia. We are proud to present this case report through a special arrangement with the Council of Associates of the College.

    TO THE EDITOR:

    Background: Pulmonary embolism is one of the leading causes of morbidity and death in the United States, with a purported 500 000 to 600 000 cases and an estimated 50 000 to 200 000 deaths occurring per year (1). The currently accepted diagnostic algorithm is integrated and includes a methodical history and physical examination supplemented by selective laboratory and radiologic testing with chest radiography; ventilation–perfusion scanning; helical computed tomography (CT); and the current gold standard, pulmonary angiography (2). Unlike these anatomic imaging methods, technetium-99m apcitide is a new physiologic imaging tool that highlights areas of acute platelet …

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