Virulence Factors Predict Escherichia coli Colonization Patterns among Human and Animal Household Members

  1. Andrew C. Murray, BS;
  2. Michael A. Kuskowski, PhD; and
  3. James R. Johnson, MD
  1. From Veterans Affairs Medical Center and University of Minnesota; Minneapolis, MN 55417.

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    TO THE EDITOR:

    Background: Urinary tract infection (UTI) is a common and costly problem for which better preventive measures are needed (1). The causative extraintestinal pathogenic Escherchia coli (ExPEC) strains usually derive immediately from the host's fecal flora (2); however, their proximal source is unknown. Sexual partners and household pets are candidate reservoirs (3, 4). Certain ExPEC virulence factors may promote host-to-host …

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