A Low-Carbohydrate, Ketogenic Diet versus a Low-Fat Diet To Treat Obesity and Hyperlipidemia
- William S. Yancy, Jr., MD, MHS;
- Maren K. Olsen, PhD;
- John R. Guyton, MD;
- Ronna P. Bakst, RD; and
- Eric C. Westman, MD, MHS
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From the Center for Health Services Research in Primary Care, Department of Veterans Affairs Medical Center, and Duke University
Medical Center, Durham, North Carolina.
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Figure 1. LCKD = low-carbohydrate, ketogenic diet; LFD = low-fat, low-cholesterol, reduced-calorie diet. Flow of participants into the study.
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Figure 2. Expected mean body weight determined by linear mixed-effects model analysis. < 0.001 for linear and quadratic time-by-diet
group interaction terms. LCKD = low-carbohydrate, ketogenic diet; LFD = low-fat, low-cholesterol, reduced-calorie diet. Expected mean body weight over time, by diet group.P
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Figure 3. The orange line represents the observed trajectory for mean body weight in the low-fat, low-cholesterol, reduced-calorie
diet ( ) group ( ) or the low-carbohydrate, ketogenic diet ( ) group ( ). At week 24, the low-fat diet group included 33 rather
than 34 participants because 1 participant contributed a blood specimen, but not weight measurements, at that time point. Individual body weight trajectories, by diet group.LCDleftLCKDright
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Appendix Figure. Low-fat, low-cholesterol, reduced-calorie diet ( ) group. Low-carbohydrate, ketogenic diet ( group). At week
24, the low-fat diet group included 33 rather than 34 participants because 1 participant contributed a blood specimen, but
not weight measurements, at that time point. The dropout mean is the mean weight loss for each diet group's dropouts who were
still in the study at that time point. The observed mean is the mean weight loss for each diet group's participants who were
still in the study at that time point. The expected mean is the mean weight loss for each diet group's participants at that
time point, by linear mixed-effects model analysis. Reasons for discontinuation and individual weight trajectories for participants who dropped out, by diet group.Top.LFDBottom.LCKD
Responses to this article
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Ann Intern Med
May 18, 2004
vol. 140
no. 10
769-777
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Figure 1. LCKD = low-carbohydrate, ketogenic diet; LFD = low-fat, low-cholesterol, reduced-calorie diet. Flow of participants into the study.
Figure 2. Expected mean body weight determined by linear mixed-effects model analysis. < 0.001 for linear and quadratic time-by-diet group interaction terms. LCKD = low-carbohydrate, ketogenic diet; LFD = low-fat, low-cholesterol, reduced-calorie diet. Expected mean body weight over time, by diet group.P
Figure 3. The orange line represents the observed trajectory for mean body weight in the low-fat, low-cholesterol, reduced-calorie diet ( ) group ( ) or the low-carbohydrate, ketogenic diet ( ) group ( ). At week 24, the low-fat diet group included 33 rather than 34 participants because 1 participant contributed a blood specimen, but not weight measurements, at that time point. Individual body weight trajectories, by diet group.LCDleftLCKDright
Appendix Figure. Low-fat, low-cholesterol, reduced-calorie diet ( ) group. Low-carbohydrate, ketogenic diet ( group). At week 24, the low-fat diet group included 33 rather than 34 participants because 1 participant contributed a blood specimen, but not weight measurements, at that time point. The dropout mean is the mean weight loss for each diet group's dropouts who were still in the study at that time point. The observed mean is the mean weight loss for each diet group's participants who were still in the study at that time point. The expected mean is the mean weight loss for each diet group's participants at that time point, by linear mixed-effects model analysis. Reasons for discontinuation and individual weight trajectories for participants who dropped out, by diet group.Top.LFDBottom.LCKD
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