Table of Contents

May 18, 2004; 140 (10)

Articles

  • A Low-Carbohydrate, Ketogenic Diet versus a Low-Fat Diet To Treat Obesity and Hyperlipidemia: A Randomized, Controlled Trial

    • William S. Yancy, Jr.,
    • Maren K. Olsen,
    • John R. Guyton,
    • Ronna P. Bakst,
    • and Eric C. Westman
    Ann Intern Med May 18, 2004 140:769-777

    Patients on a low-carbohydrate diet had better adherence and lost more weight than those on a low-fat diet. During active weight loss, serum triglyceride levels and high-density lipoprotein cholesterol levels improved more with the low-carbohydrate diet than with the low-fat diet.

  • The Effects of Low-Carbohydrate versus Conventional Weight Loss Diets in Severely Obese Adults: One-Year Follow-up of a Randomized Trial

    • Linda Stern,
    • Nayyar Iqbal,
    • Prakash Seshadri,
    • Kathryn L. Chicano,
    • Denise A. Daily,
    • Joyce McGrory,
    • Monica Williams,
    • Edward J. Gracely,
    • and Frederick F. Samaha
    Ann Intern Med May 18, 2004 140:778-785

    Participants on a low-carbohydrate diet had better results overall at 1 year than those on a low-fat, restricted-calorie diet. Weight loss was the same in the 2 groups, but patients on the low-carbohydrate diet had less atherogenic dyslipidemia and better glycemic control.

  • Metabolic Effects of Rosiglitazone in HIV Lipodystrophy: A Randomized, Controlled Trial

    • Colleen Hadigan,
    • Sigal Yawetz,
    • Abraham Thomas,
    • Fiona Havers,
    • Paul E. Sax,
    • and Steven Grinspoon
    Ann Intern Med May 18, 2004 140:786-794

    Recent studies of HIV-infected patients suggest that disordered peroxisome proliferator–activated receptor-γ (PPAR-γ) signaling pathways play a role in the pathogenesis of HIV-associated lipoatrophy. In HIV-infected patients in this study, rosiglitazone, a PPAR-γ agonist, improved lipoatrophy; insulin sensitivity; and metabolic indices, including adiponectin levels.

Improving Patient Care

  • Clarifying Adverse Drug Events: A Clinician's Guide to Terminology, Documentation, and Reporting

    • Jonathan R. Nebeker,
    • Paul Barach,
    • and Matthew H. Samore
    Ann Intern Med May 18, 2004 140:795-801

    The terminology used to describe patient harm associated with medications is confusing. This paper uses the case of a patient with multiple adverse drug events to clarify key terms, such as adverse event, adverse drug reaction, adverse drug event, medication error, and side effect.

Review

  • Meta-Analysis: Respiratory Tolerance to Regular β2-Agonist Use in Patients with Asthma

    • Shelley R. Salpeter,
    • Thomas M. Ormiston,
    • and Edwin E. Salpeter
    Ann Intern Med May 18, 2004 140:802-813

    Patients with asthma who use β2-agonists regularly for at least 1 week develop tolerance to the drug's bronchodilator and nonbronchodilator effects. Regular β2-agonist use may be associated with poorer disease control than that achieved with placebo.

In the Balance

  • Reducing Resident Work Hours: Unproven Assumptions and Unforeseen Outcomes

    • Mitchell Charap
    Ann Intern Med May 18, 2004 140:814-815

    In the 25 years that I have been teaching in New York, graduate medical education has changed a great deal. Clearly much has improved. However, the recent restrictions in work hours are an ominous development because of their effect on both patient care and the education of our future physicians.

  • Benefits of Resident Work Hours Regulation

    • Kelley M. Skeff,
    • Stephen Ezeji-Okoye,
    • Peter Pompei,
    • and Stanley Rockson
    Ann Intern Med May 18, 2004 140:816-817

    The new regulations for resident work hours, which are the most dramatic recent innovation to calibrate trainees' work hours, are one step in a long evolutionary process of change in medical education. We believe that the positive effects of the regulations are just the beginning.

  • The Effect of Work Hour Regulations on Personal Development during Residency

    • Melinda E. Glines
    Ann Intern Med May 18, 2004 140:818-819

    As I approach the halfway point of my residency, I cannot imagine why anyone coming directly out of residency would want to practice full-time, except out of financial necessity. Residency training, even in the most humane of programs, is such an all-absorbing experience that I, too, crave time to rest and reflect.

Clinical Guidelines

  • Screening for Suicide Risk: Recommendation and Rationale

    • U.S. Preventive Services Task Force*
    Ann Intern Med May 18, 2004 140:820-821

    The U.S. Preventive Services Task Force concludes that the evidence is insufficient to recommend for or against routine screening by primary care clinicians to detect suicide risk in the general population.

  • Screening for Suicide Risk in Adults: A Summary of the Evidence for the U.S. Preventive Services Task Force

    • Bradley N. Gaynes,
    • Suzanne L. West,
    • Carol A. Ford,
    • Paul Frame,
    • Jonathan Klein,
    • and Kathleen N. Lohr
    Ann Intern Med May 18, 2004 140:822-835

    Because of the complexity of studying the risk for suicide and the paucity of well-designed research studies, we have limited evidence to guide the primary care clinician's assessment and management of suicide risk.

Editorials

  • Reduced-Carbohydrate Diets: No Roll in Weight Management?

    • Walter C. Willett
    Ann Intern Med May 18, 2004 140:836-837

    In the context of the 2 studies in this issue on low-carbohydrate diets, what advice can we offer our patients who want to lose weight? We can encourage overweight patients to experiment with methods for weight control, including reduced-carbohydrate diets, as long as they emphasize healthy sources of fat and protein and incorporate regular physical activity. Patients should focus on finding ways to eat that they can maintain indefinitely rather than seeking diets that promote rapid weight loss.

  • How Many Hours Is Enough? An Old Profession Meets a New Generation

    • Steven A. Schroeder
    Ann Intern Med May 18, 2004 140:838-839

    Because the regulation limiting work hours for residents is a simple “fix” for a complicated problem and because lifestyle issues are increasingly important, we should be prepared for further attacks on the medical residency system. How medicine chooses to balance young physicians' increasingly urgent calls for a decent lifestyle with its ancient tradition of service will say a lot about what kind of a profession it will become.

On Being a Doctor

  • Obstetricians Wanted: No Mothers Need Apply

    • Lauren Plante
    Ann Intern Med May 18, 2004 140:840-841

    I was an obstetrician, and then I was a mother, until I had to give up the one for the other.

  • Dr. Mommy Blues

    • Gale Burstein
    Ann Intern Med May 18, 2004 140:842-843

    Before my own experience with postpartum depression, I was guilty of assuming stereotypes about mental health disorders. Knowing what I know today, I wonder why I had those beliefs. I wonder why more physicians are unable to be sympathetic to their colleagues' harsh realities of new motherhood and why more physicians do not thoughtfully suggest to an unhappy new-mother colleague that she may benefit from mental health services.

Letters

  • How do Physicians Think about Successful Aging?

    • Lauren Snow and
    • Cynthia X. Pan
    Ann Intern Med May 18, 2004 140:W-37

  • Cost-Effectiveness of Mammography for Older Women

    • Thomas E. Finucane
    Ann Intern Med May 18, 2004 140:844

  • Cost-Effectiveness of Mammography for Older Women

    • Jeanne Mandelblatt,
    • Somnath Saha,
    • and Mark Helfand
    Ann Intern Med May 18, 2004 140:844

  • Saving Office Practice

    • Alan R. Ertle
    Ann Intern Med May 18, 2004 140:844

  • Saving Office Practice

    • Scott Matthew Bolhack
    Ann Intern Med May 18, 2004 140:844-845

  • Saving Office Practice

    • Peter Basch
    Ann Intern Med May 18, 2004 140:845

  • Saving Office Practice

    • Harold C. Sox
    Ann Intern Med May 18, 2004 140:845

  • Management Options for Patients with Ulcer Hemorrhage

    • James Y.W. Lau and
    • Joseph J.Y. Sung
    Ann Intern Med May 18, 2004 140:845-846

  • High-Dose Vitamin C and Iron Overload

    • Bill Sardi
    Ann Intern Med May 18, 2004 140:846

  • High-Dose Vitamin C and Iron Overload

    • Kris V. Kowdley
    Ann Intern Med May 18, 2004 140:846-847

  • Actual versus Perceived Workload for House Officers: Black Cloud Looming?

    • Hobart W. Walling
    Ann Intern Med May 18, 2004 140:847-848

  • Virulence Factors Predict Escherichia coli Colonization Patterns among Human and Animal Household Members

    • Andrew C. Murray,
    • Michael A. Kuskowski,
    • and James R. Johnson
    Ann Intern Med May 18, 2004 140:848-849

  • Epinephrine-Secreting Pheochromocytoma Presenting with Cardiogenic Shock and Profound Hypocalcemia

    • Stephen W. Olson,
    • Leonard E. Deal,
    • and Michael Piesman
    Ann Intern Med May 18, 2004 140:849-851

Medical Writings: Book Notes

  • Biomedical Ethics Reviews: Stem Cell Research

    • Stuart G. Finder
    Ann Intern Med May 18, 2004 140:852

  • What I Learned in Medical School: Personal Stories of Young Doctors

    • Avery S. Hart
    Ann Intern Med May 18, 2004 140:852

Current Clinical Issues

  • Finland Pioneers International Suicide Prevention

    • Jennifer Fisher Wilson
    Ann Intern Med May 18, 2004 140:853-856

Ad Libitum

Book Listings

  • Book Listings

    Ann Intern Med May 18, 2004 140:0

Medical Notices

  • Medical Notices

    Ann Intern Med May 18, 2004 140:0

Summaries for Patients

  • Effectiveness and Safety of Low-Carbohydrate Diets

    Ann Intern Med May 18, 2004 140:I-10

  • Weight Loss and Results of Low-Carbohydrate Diets

    Ann Intern Med May 18, 2004 140:I-27

  • Rosiglitazone Treatment for Fat Redistribution and Metabolic Abnormalities Caused by Anti-HIV Therapy

    Ann Intern Med May 18, 2004 140:I-36

  • Tolerance to Beta2-Agonist Treatment after Regular Use in People with Asthma

    Ann Intern Med May 18, 2004 140:I-41

  • Screening To Identify Primary Care Patients Who Are at Risk for Suicide: Recommendations from the U.S. Preventive Services Task Force

    Ann Intern Med May 18, 2004 140:I-49
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This Issue

May 18, 2004; 140 (10)
  1. Articles
  2. Improving Patient Care
  3. Review
  4. In the Balance
  5. Clinical Guidelines
  6. Editorials
  7. On Being a Doctor
  8. Letters
  9. Medical Writings: Book Notes
  10. Current Clinical Issues
  11. Ad Libitum
  12. Book Listings
  13. Medical Notices
  14. Summaries for Patients

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