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HFE Gene Mutations in Chile
- Nelson Wohllk, MD;
- Rodrigo Zapata, MD;
- Mónica Acuña, MSc;
- Humberto Reyes, MD;
- Alex Navarro, MD;
- Iván Roa, MD; and
- Juan Carlos Roa, MD
- From University of Chile School of Medicine Casilla 16038, Santiago, Chile; University of Valparaíso and Chilean Air Force Hospital Casilla 27013, Santiago, Chile; and Universidad de La Frontera Casilla 54-D, Temuco, Chile. Grant Support: By grants 1980135 and 1010648 from Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT).
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TO THE EDITOR:
Background: The prevalence of hereditary hemochromatosis varies among countries and geographic regions, apparently influenced by the ethnic origin of the local population and by the prevalence of allele variants C282Y and H63D in the HFE gene on chromosome 6 (1, 2). The current population of Chile is predominantly white but includes vestiges of an …
