This year's Update in Hematology focuses on 3 exciting topics in the field: nonablative hematopoietic stem-cell transplantation,
therapy targeted at specific alterations in cancer cells, and stem-cell plasticity. Groundbreaking research in the first 2
areas is changing standards of hematology care. The third area, hematopoietic stem-cell plasticity, is showing some early
potential for future therapy.